Uji Aktivitas Antibakteri Ekstrak Etanol Kulit Batang Delima (Punica granatum. L)Terhadap Bakteri Staphylococus aureus ATCC 6538 Tahun 2016
DOI:
https://doi.org/10.31965/infokes.Vol16.Iss1.184Keywords:
Pomegranate bark, Punica granatum, L, Ethanol extractAbstract
Background: Pomegranate bark (Punica granatum, L) contains ellagitannin, triterpenoid, alkaloids consisting of pelletierine, methylpelletieren, pseudopelletierine, flavonoids, and saponins. Substances that are able to inhibit bacterial growth are saponins and flavonoids.
Objective: to determine the antibacterial activity of ethanol extract of pomegranate bark (Punicagranatum, L) on the Staphylococcus aureus bacteria.
Method: The manufacture of pomegranate bark extract was carried out using the Soxlhetasi method, after extracting the antibacterial activity was carried out by using a cylinder diffusion method.
Result: Ethanol extract of pomegranate bark (Punica granatum, L) has antibacterial activity against Staphylococcus aureus bacteria at a concentration of 10% b / v, 25% b / v, 50% b / v and 75% b / v with each inhibition zone diameter -as equal to 18.70 mm, 21.00 mm, 22.30 mm and 26.20 mm. Stastically, ethanol extract of pomegranate bark (Punica granatum, L) has significant antibacterial power with p = 0.001 (p <0.05).
Conclusion: Ethanol extract of pomegranate bark (Punica granatum, L) has antibacterial activity against Staphylococcus aureus bacteria with very strong concentration is a concentration of 25% b / v, 50% b / v and 75% b / v, because the inhibition zone is> 20 mm.
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References
Davis, W.W. dan T.R. Stout.1971. Disc Plate Methods of Microbiological Antibiotic Assay. Microbiology 22.
Fransiska. Ekstrak Etanol Kulit Buah Delima Putih dalam Menghambat Pertumbuhan Bacillus Subtilis dan Escherichia Coli secara in vitro. Fakultas Kedokteran Gigi Universitas Brawijaya. 2009
Jawetz, E., Melnick, & Adelberg, 2005, Mikrobiologi Kedokteran, 234-235, 317- 318, 321, Penerbit Salemba Medika. Jakarta.
Neal, M. J., 2006, At a Glance Farmakologis Medis, Edisi kelima, diterjemahkan oleh Safitri, A., 81, 83-84, Penerbit Erlangga. Jakarta.
Robinson T, 1995. Kandungan Organik Tumbuhan Tinggi. Bandung: Institut Teknologi Bandung Press.
Syamsuhidayat, S. dan Hutapea, R. 2001, Inventaris Tanaman Obat Indonesia. Jakarta: Depkes RI.
Waluyo, L., 2004, Mikrobiologi Umum, UMM press. Malang.
Tambekar, D. H dan Dahikar, S.B. 2010. Exploring antibacterial potential Of some ayurvedic preparations to control. Journal of Chemical Pharmaceutical Research .2 (5): 494-501
Setyaningrum, G. 2005. Aktivitas Antidiabetes Eskrak Air dan Etanol Daun Kaca
Piring (Gardenia jasminoides ellis). Tesis: Institut Teknologi Bandung
Cushnie TPT; Hamilton, VES and Lamb, AJ. 2003. Assessment of the antibacterial activity of selected flavonoids and consideration of discrepancies between previous reports. Microbiol Res.158: 281–289
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