Nausea and Vomiting of Pregnancy: Multiple Contributing Factors

Authors

  • Sri Wahyuni Doctoral Program of Medicine and Health Sciences, Faculty of Medicine, University of Diponegoro, Semarang, Central Java, Indonesia
  • Noor Pramono Faculty of Medicine, University of Diponegoro, Semarang, Central Java, Indonesia
  • Suharyo Hadisaputro Faculty of Medicine, University of Diponegoro, Semarang, Central Java, Indonesia
  • Annastasia Ediati Faculty of Psychology, University of Diponegoro, Semarang, Central Java, Indonesia

DOI:

https://doi.org/10.31965/infokes.Vol21.Iss4.1388

Keywords:

NVP, Risk factor, first trimester

Abstract

Nausea and vomiting are common conditions in earlier pregnancy. Some studies have suggested that nausea and vomiting during pregnancy (NVP) is caused by multiple factors, however, few studies assessed family support and psychological factors. The present study aimed to assess the prevalence of NVP and its contributing factors. A cross-sectional study was conducted in five Primary Health Centers in Semarang during August 2023. A total of 99 eligible pregnant women were included. A logistic regression was used to determine the significant contributing factors of NVP. The prevalence of moderate to severe and mild NVP was 71.7% and 28.3% respectively. Bivariate analysis indicated that gestational age and anxiety level significantly influence NVP (p-value <0.05). Women with greater gestational age (OR= 2.462; 0.954-6.356) and mild anxiety (OR=3.337; 1.240-8.982) were more likely to experience NVP during their pregnancy. Gestational of 12 weeks and mild anxiety are strongly associated with NVP. These findings highlight the crucial of psychological factors despite other health-related conditions.

Downloads

Download data is not yet available.

References

Bray, N., Grasby, K. L., Lind, P. A., Painter, J. N., Colodro-Conde, L., & Medland, S. E. (2021). The psychosocial impact of nausea and vomiting during pregnancy as a predictor of postpartum depression. Journal of Health Psychology, 26(7), 1061–1072. https://doi.org/10.1177/1359105319859048

Bustos, M., Venkataramanan, R., & Caritis, S. (2017). Nausea and vomiting of pregnancy-What's new?. Autonomic Neuroscience, 202, 62-72. https://doi.org/10.1016/j.autneu.2016.05.002

Chan, R. L., Olshan, A. F., Savitz, D. A., Herring, A. H., Daniels, J. L., Peterson, H. B., & Martin, S. L. (2011). Maternal influences on nausea and vomiting in early pregnancy. Maternal and Child Health Journal, 15(1), 122–127. https://doi.org/10.1007/s10995-009-0548-0

Clark, D. B., & Donovan, J. E. (1994). Reliability and Validity of the Hamilton Anxiety Rating Scale in an Adolescent Sample. Journal of the American Academy of Child and Adolescent Psychiatry, 33(3), 354–360. https://doi.org/10.1097/00004583-199403000-00009

Davis, M. (2004). Nausea and vomiting of pregnancy: an evidence-based review. The Journal of perinatal & neonatal nursing, 18(4), 312-328.

Deatsman, S., Vasilopoulos, T., & Rhoton-Vlasak, A. (2016). Age and fertility: A study on patient awareness. Jornal Brasileiro de Reproducao Assistida, 20(3), 99–106. https://doi.org/10.5935/1518-0557.20160024

Dekkers, G. W. F., Broeren, M. A. C., Truijens, S. E. M., Kop, W. J., & Pop, V. J. M. (2019). Hormonal and psychological factors in nausea and vomiting during pregnancy. Psychological Medicine, 50(2), 229–236. https://doi.org/10.1017/S0033291718004105

Erick M, Cox JT, & Mogensen KM. (2018). ACOG Practice Bulletin 189: Nausea and Vomiting of Pregnancy. Obstet Gynecol, 131(5), 935. https://doi.org/10.1097/AOG.0000000000002604

Gemayel, D., Wiener, K. K. K., & Saliba, A. (2021). The development and validation of the Multidimensional Paternal Perinatal Scale (MPPS). Heliyon, 7(5). https://doi.org/10.1016/j.heliyon.2021.e06978

Hada, A., Minatani, M., Wakamatsu, M., Koren, G., & Kitamura, T. (2021). The pregnancy-unique quantification of emesis and nausea (Puqe-24): Configural, measurement, and structural invariance between nulliparas and multiparas and across two measurement time points. Healthcare (Switzerland), 9(11). https://doi.org/10.3390/healthcare9111553

Hamilton, M. (1959). The assessment of anxiety states by rating. Br J Med Psychol, 32, 50–55. https://doi.org/10.1111/j.2044-8341.1959.tb00467.x

Hizli, D., Kamalak, Z., Kosus, A., Kosus, N., & Akkurt, G. (2012). Hyperemesis gravidarum and depression in pregnancy: Is there an association? Journal of Psychosomatic Obstetrics and Gynecology, 33(4), 171–175. https://doi.org/10.3109/0167482X.2012.717129

Jennings, L. K., & Mahdy, H. (2023). Hyperemesis Gravidarum. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK532917/

Junandar, C. Y., Wittiarika, I. D., Utomo, B., & Ernawati, E. (2021). The Relationship of Social Support with The Degree of Nausea and Vomiting in Pregnancy. Indonesian Midwifery and Health Sciences Journal, 4(1), 26–32. https://doi.org/10.20473/imhsj.v4i1.2020.26-32

Lee, N. M., & Saha, S. (2011). Nausea and vomiting of pregnancy. Gastroenterology Clinics, 40(2), 309-334. https://doi.org/10.1016/j.gtc.2011.03.009

Liu, C., Zhao, G., Qiao, D., Wang, L., He, Y., Zhao, M., ... & Jiang, E. (2022). Emerging progress in nausea and vomiting of pregnancy and hyperemesis gravidarum: challenges and opportunities. Frontiers in Medicine, 8, 809270. https://doi.org/10.3389/fmed.2021.809270

Niemeijer, M. N., Grooten, I. J., Vos, N., Bais, J. M. J., Van Der Post, J. A., Mol, B. W., Roseboom, T. J., Leeflang, M. M. G., & Painter, R. C. (2014). Diagnostic markers for hyperemesis gravidarum: A systematic review and metaanalysis. American Journal of Obstetrics and Gynecology, 211(2), 150.e1-150.e15. https://doi.org/10.1016/j.ajog.2014.02.012

Nurmi, M., Rautava, P., Gissler, M., Vahlberg, T., & Polo-Kantola, P. (2020). Incidence and risk factors of hyperemesis gravidarum: A national register-based study in Finland, 2005-2017. Acta Obstetricia et Gynecologica Scandinavica, 99(8), 1003–1013. https://doi.org/10.1111/aogs.13820

Oktavia, L. (2016). Kejadian Hiperemisis Gravidarum Ditinjau dari Jarak Kehamilan dan Paritas. Jurnal Ilmu Kesehatan Aisyah, 1(2), 42. https://doi.org/10.30604/jika.v1i2.19

Retni, A., Handayani, F., & Mohamad, I. S. W. (2020). Literature Review : Pemberian Aromaterapi Essential Oil Lavender Terhadap Emesis Gravidarum Pada Kehamilan Trimester Pertama. Journal of Borneo Holistic Health, 3(2), 141. https://doi.org/10.35334/borticalth.v3i2.1687

Retnowati, Y. (2019). Faktor - Faktor Yang Memperngaruhi Terjadinya Emesis Gravidarum Pada Kehamilan Trimester I Di Puskesmas Pantai Amal. Journal of Borneo Holistic Health, 2(1), 40–56. https://doi.org/10.35334/borticalth.v2i1.586

Roberts, K., Havlíček, J., Kaňková, Š., Klapilová, K., & Roberts, S. C. (2023). Testing effects of partner support and use of oral contraception during relationship formation on severity of nausea and vomiting in pregnancy. BMC Pregnancy and Childbirth, 23(1), 175. https://doi.org/10.1186/s12884-023-05468-x

Royal College of Obstetricians and Gynaecologists. (2016). The Management of Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum. Royal College of Obstetricians and Gynaecologists.

Şahin, B., Özçetinkaya Erdoğan, S., Cura Şahin, G., Karlı, P., Kara, O. F., Hatırnaz, Ş., & Tinelli, A. (2022). Nausea and vomiting during pregnancy: a possible correlation with obsessive compulsive disorder and alexithymia. Journal of Obstetrics and Gynaecology, 42(5), 929–934. https://doi.org/10.1080/01443615.2021.1960492

Schetter, C. D., & Tanner, L. (2012). Anxiety, depression and stress in pregnancy: implications for mothers, children, research, and practice. Current opinion in psychiatry, 25(2), 141–148). https://doi.org/10.1097/YCO.0b013e3283503680

Taguchi, K., Shinohara, H., & Kodama, H. (2022). A longitudinal investigation of the influence of psychological factors on nausea and vomiting in early pregnancy. Archives of Women’s Mental Health, 25(5), 995–1004. https://doi.org/10.1007/s00737-022-01262-4

Tan, P. C., Tan, N. C., & Omar, S. Z. (2009). Effect of high levels of human chorionic gonadotropin and estradiol on the severity of hyperemesis gravidarum. Clinical Chemistry and Laboratory Medicine, 47(2), 165–171. https://doi.org/10.1515/CCLM.2009.041

Tan, P. C., Zaidi, S. N., Azmi, N., Omar, S. Z., & Khong, S. Y. (2014). Depression, anxiety, stress and hyperemesis Gravidarum: Temporal and case controlled correlates. PLoS ONE, 9(3). https://doi.org/10.1371/journal.pone.0092036

Uguz, F., Gezginc, K., Kayhan, F., Cicek, E., & Kantarci, A. H. (2012). Is hyperemesis gravidarum associated with mood, anxiety and personality disorders: A case-control study. General Hospital Psychiatry, 34(4), 398–402. https://doi.org/10.1016/j.genhosppsych.2012.03.021

Wang, H., Rolls, E. T., Du, X., Du, J., Yang, D., Li, J., Li, F., Cheng, W., & Feng, J. (2020). Severe nausea and vomiting in pregnancy: Psychiatric and cognitive problems and brain structure in children. BMC Medicine, 18(1), 228. https://doi.org/10.1186/s12916-020-01701-y

Yilmaz, T., Dinç Kaya, H., Günaydin, S., Güdücü, N., & Dişsiz, M. (2022). Psychometric properties of the Pregnancy-Unique Quantification of Emesis (PUQE-24) scale. Journal of Obstetrics and Gynaecology, 42(6), 1739–1745. https://doi.org/10.1080/01443615.2022.2036961

Zhang, H., Wu, S., Feng, J., & Liu, Z. (2020). Risk factors of prolonged nausea and vomiting during pregnancy. Risk Management and Healthcare Policy, 13, 2645–2654. https://doi.org/10.2147/RMHP.S273791

Downloads

Published

2023-12-31

How to Cite

Wahyuni, S., Pramono, N., Hadisaputro, S., & Ediati, A. (2023). Nausea and Vomiting of Pregnancy: Multiple Contributing Factors. JURNAL INFO KESEHATAN, 21(4), 681–688. https://doi.org/10.31965/infokes.Vol21.Iss4.1388

Issue

Section

Original Articles

Most read articles by the same author(s)

Similar Articles

1 2 3 4 5 6 7 8 9 > >> 

You may also start an advanced similarity search for this article.