Mapping Hepatitis B Infection in Cap Tikus Consumers in South Minahasa, North Sulawesi
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Risk factors for alcohol consumption can accelerate the development of hepatitis B infection leading to liver fibrosis, cirrhosis, and even Hepatocellular Carcinoma (HCC). North Sulawesi is the second province with the highest number of alcohol drinkers in Indonesia. Cap Tikus is a traditional community drink which is traditionally made from palm tree liquid. The tradition of drinking Cap Tikus is usually done by consuming it together in the same glass; where this behavior is risky behavior for the transmission of hepatitis B infection. Therefore, this research was conducted to determine the distribution of hepatitis B infection based on the results of the HBsAg examination in the South Minahasa area. The research design is quantitative with a descriptive research type. The population of the study was Cap Tikus drinkers in six locations in South Minahasa Regency. The sample consisted of 309 respondents, found through a random sampling technique based on inclusion and exclusion criteria. The research variable was the result of the HBV examination using the Enzyme Link Immunosorbent Assay (ELISA) method. The results showed that 67.6% of respondents were in the age range of 30-50 years, and 50.1% worked as farmers. The majority of respondents (31.7%) consumed Cap Tikus 3 times a week, with an alcohol level of 45-50% as many as 47.9 respondents; 41.1% of respondents consumed 250-350 ml in one drink. The results of the ELISA reader examination showed that 4 respondents (1.3%) gave results above the cut-off value of 1.007. Based on the results of the research conducted, this study concludes that as many as 1.3% of respondents were declared positive for HBsAg through the ELISA examination and were only found in Ranomea Village, South Minahasa Regency. It is hoped that the government and health workers will be able to provide health education about the dangers of drinking alcohol excessively and educate about the risk factors for transmission of the hepatitis B virus.
Abassa, K. K., Wu, X. Y., Xiao, X. P., Zhou, H. X., Guo, Y. W., & Wu, B. (2022). Effect of alcohol on clinical complications of hepatitis virus-induced liver cirrhosis: a consecutive ten-year study. BMC Gastroenterology, 22(1), 1–12. https://doi.org/10.1186/s12876-022-02198-w
Alhajj, M., Zubair, M., & Farhana, A. (2023). Enzyme Linked Immunosorbent Assay. StatPearls Publishing. Retrieved from: https://www.ncbi.nlm.nih.gov/books/NBK555922/
Andayani, I. G. A. S., Rizki, M., Sriasih, M., & Tauhida, I. N. (2023). Performa Rapid Diagnostik Tes Hepatitis B dengan ELISA sebagai Gold Standar. Bioscientist : Jurnal Ilmiah Biologi, 11(2), 1263. https://doi.org/10.33394/bioscientist.v11i2.9035
Chen, Q., Liu, J., He, Y., Yang, L., Luo, H., Wang, Y., Zhang, X., & Li, N. (2021). Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study. PLoS ONE, 16(November), 1–11. https://doi.org/10.1371/journal.pone.0260028
Dolonseda, H. P., & Palangda, L. (2023). Kajian Ekonomi Produksi Usaha Cap Tikus di Masyarakat Desa Beringin, Kecamatan Ranayapo, Kabupaten Minahasa Selatan. 06(01), 10011–10018. Retrieved from: https://jonedu.org/index.php/joe/article/view/4667
Firdayanti, F., Rahmawati, N., Susanti, S., & Aulya, M. S. (2024). Skrining Hepatitis B Pada Pengonsumsi Alkohol Di Desa Tapunggaya Kecamatan Molawe. Sentri: Jurnal Riset Ilmiah, 3(2), 1034–1040. Retrieved from: https://doi.org/10.55681/sentri.v3i2.2284
Ganesan, M., Eikenberry, A., Poluektova, L. Y., Kharbanda, K. K., & Osna, N. A. (2020). Role of alcohol in pathogenesis of hepatitis B virus infection. World Journal of Gastroenterology, 26(9), 883–903. https://doi.org/10.3748/wjg.v26.i9.883
Ghosh, M., Nandi, S., Dutta, S., & Saha, M. K. (2015). Detection of hepatitis B virus infection: A systematic review. World Journal of Hepatology, 7(23), 2482–2491. https://doi.org/10.4254/wjh.v7.i23.2482
Hay, S. I., & Snow, R. W. (2006). The Malaria Atlas Project: Developing global maps of malaria risk. PLoS Medicine, 3(12), 2204–2208. https://doi.org/10.1371/journal.pmed.0030473
Hossain, B., Sultana, S., Alam, B., Bari, A., & Awal, R. (2024). Risk Factors and Transmission Patterns of Hepatitis B Virus Among Hospitalized Patients. The Insight, 7(02), 22–26. Retrieved from: https://bdjournals.org/index.php/insight/article/view/634
Kishore, S., Ravi, S., Kishore, S., Pasi, R., & Verma, N. (2019). Prevalence of alcohol consumption among adults & elderly- A community based study in Uttarakhand. Indian Journal of Community Health, 31(1), 118–122. https://doi.org/10.47203/ijch.2019.v31i01.019
Li, T. Y., Yang, Y., Zhou, G., & Tu, Z. K. (2019). Immune suppression in chronic hepatitis B infection associated liver disease: A review. World Journal of Gastroenterology, 25(27), 3527–3537. https://doi.org/10.3748/wjg.v25.i27.3527
Lintong, L. V, Deeng, D., & Mamosy, W. (2022). Perubahan Nilai Budaya Masyarakat Cap Tikus Di Desa Talaitad Utara Kecamatan Suluun Tareran Kabupaten Minahasa Selatan. HOLISTIK, Journal of Social and Culture, 15(4), 1–14. Retrieved from: https://ejournal.unsrat.ac.id/v3/index.php/holistik/article/view/45409
Mehta, P., Grant, L. M., & Reddivari, A. K. R. (2024). Viral Hepatitis. StatPearls Publishing. Retrieved from: https://www.ncbi.nlm.nih.gov/books/NBK554549/
Öner, P., Yılmaz, S., Kılıç, N., & Özsoy, F. (2022). Seroprevalence of HBsAg, Anti-HBs, Anti-HCV, and Anti-HIV in patients with alcohol and substance abuse in an amatem clinic in eastern turkiye: a six-year retrospective evaluation. Journal of Contemporary Medicine, 12(6), 959-965. https://doi.org/10.16899/jcm.1189072
Onyia, N. E., Okoh, M., Omoregie, F. O., Ugiagbe, R. A., & Ayinbuomwan, E. (2024). Accuracy of Saliva as a Diagnostic Medium for Hepatitis B Virus Infection: A Quantitative ELISA Analysis. Nigerian Journal of Basic and Clinical Sciences, 21(1), 73–78. https://doi.org/10.4103/njbcs.njbcs_64_23
Parke, H., Michalska, M., Russell, A., Moss, A. C., Holdsworth, C., Ling, J., & Larsen, J. (2018). Understanding drinking among midlife men in the United Kingdom: A systematic review of qualitative studies. Addictive Behaviors Reports, 8(May), 85–94. https://doi.org/10.1016/j.abrep.2018.08.001
Rintjap, D. S., Banne, Y., Barung, E. N., EKalonio, D., MNahor, E., & Terok, M. Y. (2023). Identifikasi Metanol Dalam Minuman Beralkohol Dari Hasil Fermentasi Air Nira (Cap Tikus) Di Manado. Prosiding Seminar Nasional Dies Natalis Poltekkes Kemenkes Manado XXII, 91–94. Retrieved from: https://ejurnal.poltekkes-manado.ac.id/index.php/prosiding2023/article/download/1954/1181
Roerecke, M., Vafaei, A., Hasan, O. S., Chrystoja, B. R., Cruz, M., Roy, L., Neuman, M. G., & Rehm, J. (2019). Alcohol consumption and risk of liver cirrhosis: a systematic review and meta-analysis. Am J Gastroenterol, 114(10), 1574–1586. https://doi.org/10.14309/ajg.0000000000000340
Serikova, E. N., Semenov, A. V., Ostankova, Y. V., & Totolian, A. A. (2021). Method for detecting hepatitis B virus in blood plasma at low viral load using real-time PCR. Klinicheskaia Laboratornaia Diagnostika, 66(1), 59–64. https://doi.org/10.18821/0869-2084-2021-66-1-59-64
Tambayong, N. F., Laoh, O. E. H., & Porajouw, O. (2016). Analisis Usaha Cap Tikus Di Desa Poopo Kecamatan Passi Timur Kabupaten Bolaang Mongondow. Agri-Sosioekonomi, 12(2), 77–86. https://doi.org/10.35791/agrsosek.12.2.2016.12272
Badan Kebijakan Pembangunan Kesehatan. (2023). Survei Kesehatan Indonesia (SKI) Dalam Angka Dalam Angka. Jakarta: Badan Kebijakan Pembangunan Kesehatan. Retrieved from: https://www.badankebijakan.kemkes.go.id/ski-2023-dalam-angka/
Badan Penelitian dan Pengembangan Kesehatan. (2019). Laporan Provinsi Sulawesi Utara RISKESDAS Tahun 2018. Jakarta: Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia.
Tripathi, N., & Mousa, O. Y. (2023). Hepatitis B. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK555945/
World Health Organization. (2017). Guidelines on Hepatitis B and C Testing. Geneva: WHO. Retreived from: https://iris.who.int/bitstream/handle/10665/254621/9789241549981-eng.pdf?sequence=1
World Health Organization. (2024). Global Hepatitis Report 2024. World Health Organization Retrieved from: https://www.who.int/publications/i/item/9789240091672
World Health Organization. (2024). Alcohol. World Health Organisation. Retrieved from: https://www.who.int/news-room/fact-sheets/detail/alcohol
Xu, H. Q., Wang, C. G., Zhou, Q., & Gao, Y. H. (2021). Effects of alcohol consumption on viral hepatitis B and C. World Journal of Clinical Cases, 9(33), 10052–10063. https://doi.org/10.12998/WJCC.V9.I33.10052
Zhou, E., Yang, C., & Gao, Y. (2021). Effect of alcohol on the progress of Hepatitis B cirrhosis. Annals of Palliative Medicine, 10(1), 415–424. https://doi.org/10.21037/apm-20-2353
Zinszer, K., Verma, A. D., Charland, K., Brewer, T. F., Brownstein, J. S., Sun, Z., & Buckeridge, D. L. (2012). A scoping review of malaria forecasting: Past work and future directions. BMJ Open, 2(6), 1–11. https://doi.org/10.1136/bmjopen-2012-001992
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