Formula dan Manfaat Daun Mindi (Melia Azedarach L) sebagai Antidiabetes: Tinjauan Pustaka

Authors

  • Ineke Noviana Poltekkes Kemenkes Kupang, Indonesia
  • Yosephina E S Gunawan Poltekkes Kemenkes Kupang, Indonesia
  • Veronika Toru Poltekkes Kemenkes Kupang, Indonesia
  • Wahyudi RSUD Mardi Waluyo Kota Blitar, Indonesia
  • Maria Ch. Endang Sukartiningsih Poltekkes Kemenkes Kupang, Indonesia

DOI:

https://doi.org/10.31965/jkp.v8iSpecial%20Edition.1770

Keywords:

Mindi leaves, diabetic, literature review

Abstract

Background: The International Diabetes Federation (IDF) estimates that there will be an increase in the number of people with DM in Indonesia from 9.1 million in 2014 to 14.1 million in 2035. With this figure, Indonesia is ranked 5th in the world. According to the 2013 Basic Health Research, the proportion of DM was 6.9% and was 10.9% in 2018. The increasing DM population has resulted in various complications including retinopathy, neuropathy and other complications. In one study it was found that diabetes patients with a history of diabetic ulcers had a 47% increased risk of death. Objective: the purpose of this literature review research is to obtain a theoretical overview of the results of other people's research that can support the solution of the problem being handled carefully. Method: A research method that searches and examines several journals or articles related to the subject of research to create a written work on a certain topic. Method: The method in this research is a literature review which contains descriptive findings from others research. Results: search for articles discussed in this research were 2 national journals and 3 international journals. In the article discussed, the results show that mindi has good antioxidant content, contains flavonoids and can reduce sugar levels. From laboratory and experimental tests, the results produced are significant in reducing sugar levels and contain flavonoids which are useful in warding off free radicals.

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References

Achmad (2015). Konsensus Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 Jakarta, PB PERKENI.

Asadujjaman (2013). "Assessment of Bioactivities of Ethanolic Extract of Melia azedarach Leaves " Coastal Life Medicine 1, 118122.

Bhattacharya S, M. S., Pramnaick D, Hazra AK, Choudhury M (2016). "HPLC of a phenolic compound, antioxidant and antimicrobial activity of bulbs from three ornithagalum species available in India." Int J Pharm Pharm Sci 8: 187-192.

Bilous R, D. R. (2014). Buku pegangan diabetes. Jakarta, Bumi Medika.

Listoyo, A. B., Kusrini, D. Fachriyah, E (2018). "Isolasi Asam Ferulat Dari Daun Mindi (Melia azedarach L.) Dan Uji Aktivitas Antioksidan." JKPK (Jurnal Kimia Dan Pendidikan Kimia) Vol 3, No 1 Tahun 2018 Program Studi Pendidikan Kimia Universitas Sebelas Maret https://jurnal.uns.ac.id/jkpk.

Maroua Akacha, L. K. a. N. G. B. (2016). "Phytochemically evaluation and net anti-oxidant activity of Tunisian Melia azedarach leaves extract from their ProAntidex parameter." A Journal of the Bangladesh Pharmacological Society (BDPS) 11: 301-307.

Maroua Akacha, L. K. a. N. G. B. (2016). "Phytochemically evaluation and net anti-oxidant activity of Tunisian Melia azedarach leaves extract from their ProAntidex parameter." A Journal of the Bangladesh Pharmacological Society (BDPS): 301-307.

Marzali (2016). "Menulis Kajian Literatur." Jurnal Etnografi Indonesia 1(2), 27.

Md. Asadujjaman, A. S., Md. Aslam Hossain, Utpal Kumar Karmakar (2013). "Assessment of bioactivities of ethanolic extract of Melia azedarach (Meliaceae) leaves." Journal of Coastal Life Medicine.

Mishra (2013). "Melia azedarach: A Review " Medicinal Chemistry and analysis 3(2) : 53-56.

Rahmawati, F. (2016). "Skrining Diabetes Mellitus Gestasional dan Faktor Risiko yang Mempengaruhinya " Keperawatan Sriwijaya ISSN 2355 5459 3(2).

Rama R Nargund, V. H. K., Prasanna V Habbu, Joshi AB, Goude T and Smita D Madagundi (2018). "Isolation, characterization of seconadry metabolites from the Melia azedarach Linn. Root and to evaluate their in vitro antidiabetic activity." Journal of Pharmacognosy and Phytochemistry 7(1): 2214-2220.

Robert J. Snyder, D., CWSRobert S. Kirsner, MD, PhDRobert A. Warriner III, MD, FACA, FCCP, FCCWS, ABPM/UHMLawrence A. Lavery, DPM, MPHJason R. Hanft, DPM, FACFASPeter Sheehan, MD (2010). "Consensus Recommendations OnAdvancing The Standard Of CareFor Treating Neuropathic FootUlcers In Patients With Diabetes."

Santoso (2015). Pemberian Ekstrak Etanol Daun Afrika Selatan Oral Meningkatkan Kadar Insulin Puasa dan Menurunkan Kadar Glukosa Darah Post Prandial pada Tikus Putih antan Diabetes Melitus. Universitas Udayana, Ilmu Biomedik.

Sari, L. R. (2011). "Pengaruh Daun Mindi (Melia Azedarach L.) Terhadap Kadar Gula Darah Dengan Menggunakan Tikus Jantan (Rattus Norvegicus)." Jurnal Ilmu-Ilmu Kesehatan Surya Medika 7.

Seifu, D. "Antidiabetic and gastric emptying inhibitory effect of herbal Melia azedarach leaf extract in rodent models of diabetes type 2 mellitus."

Sharma, D. a. Y. P. (2013). "Preliminary and Pharmacologcal Profile of Melia azedarach L: An owerview." Applied Pharmaceutical Science 3(12), 133-138.

Siti (2018). Uji Aktivitas Antidiabetes Ekstrak Etanol Daun Sirih Merah (Piper crocatum) Terhadap Tikus Putih Jantan Galur Wistar Yang Diinduksi Aloksan, Skripsi. Fakultas farmasi ; Surakarta.

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Published

2023-08-30

How to Cite

Noviana, I., Gunawan, Y. E. S., Toru, V., Wahyudi, & Sukartiningsih, M. C. E. (2023). Formula dan Manfaat Daun Mindi (Melia Azedarach L) sebagai Antidiabetes: Tinjauan Pustaka. JKP (Jurnal Kesehatan Primer), 8(Special Edition), 49–55. https://doi.org/10.31965/jkp.v8iSpecial Edition.1770

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Vol. 8 No. Special Edition (2023): JKP (Jurnal Kesehatan Primer)

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